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Searching for flights from San Francisco to Rome? Discover wego.com's selection of low-cost San Francisco to Rome flights. These carriers have been selected for their discount prices on air tickets to Rome, get the best airfares to Rome with one click and compare flight deals.

These San Francisco airport(s) service flights on the San Francisco to Rome route:

San Francisco International Airport (SFO)

These Rome airport(s) service flights on the Rome to San Francisco route:

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If you also need a hotel in Rome don't forget that wego.com has the best selection of hotel deals in Rome.

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